Research Article

Citrus junos Tanaka Peel Extract Exerts Antidiabetic Effects via AMPK and PPAR- both In Vitro and In Vivo in Mice Fed a High-Fat Diet

Figure 1

Effect of ethanol extract of yuja pulp (YpEE), ethanol extract of yuja peel (YPEE), water extract of yuja pulp (YpWE), and water extract of yuja peel (YPWE) on glucose uptake in C2C12 myotubes. Cells were treated with the indicated stimulus in a dose-dependent manner, and then, the 2-NBDG uptake assay was performed, as described in Section 2 (a). Data are expressed as mean SD. versus none. HPLC was performed as described in Section 2. Peaks: A, chlorogenic acid; B, caffeic acid; C, epicatechin; D, rutin; E, luteolin-7-glucoside; F, naringin; G, hesperidin; H, quercetin; I, naringenin; J, kemperol; K, apegenin-7-glucoside; L, Tangeretin. STD, standard; YPEE, ethanol extract of yuja peel (b).