Topical Administration of Manuka Oil Prevents UV-B Irradiation-Induced Cutaneous Photoaging in Mice
Manuka oil suppresses UV-B-induced increase in epidermal thickness. (a) Representative photographs of haematoxylin and eosin stained dorsal skin sections taken at the end of the experiment from the no UV-B irradiation control (no UV-B) group, vehicle only group (vehicle), and the group that received 10% manuka oil (manuka oil), respectively. Magnification: 200x fold; scale bar: 200 μm. (b) The relative values of epidermal thickness are estimated from the digital photoimages of haematoxylin and eosin stained sections and depicted as mean ± SEM ( per group). ##: significantly different from no UV-B control group (). **: significantly different from vehicle only group ().