Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 2

Research Article

Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice

Figure 2

The effect of functional ES components on glucose uptake in C2C12 myotubes and insulin-resistant 3T3-L1 cells. (a) C2C12 myotubes were treated for 24 h with 10 μM of each compound and glucose uptake was measured in basal and insulin exposure conditions. * versus basal control. # versus insulin-treated control. CTL, control; SY, syringin; EE, eleutheroside E; ISO, isoflaxidin. (b) For insulin resistance conditions, 20 ng/mL TNF-α was added for 6 h in differentiated 3T3-L1 cells. After treatment with 10 μM EE for 24 h, glucose uptake was measured. * versus control. Results are the mean ± SD of 6 wells in each group. Each experiment was repeated at least three times.

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