A Phenylbutenoid Dimer, <i>cis</i>-3-(3′,4′-Dimethoxyphenyl)-4-[(<i>E</i>)-3′′′,4′′′-Dimethoxystyryl] Cyclohex-1-ene, Exhibits Apoptogenic Properties in T-Acute Lymphoblastic Leukemia Cells via Induction of p53-Independent Mitochondrial Signalling Pathway

<table>Flow cytometric analysis of cell cycle phase distribution of CEMss cells treated with ZC-B11 (IC<sub>50</sub>) in a time-dependent manner. (a) Control, (b) 24 h, (c) 48 h, and (d) 72 h. Region I is “sub-G0/G1” peak denoting apoptotic cells with hypodiploid DNA content, Region II is “G0/G1” phase, Region III is S phase, and Region IV is “G2/M” phase.</table>

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Figure 4

Figure 4: A Phenylbutenoid Dimer, <i>cis</i>-3-(3′,4′-Dimethoxyphenyl)-4-[(<i>E</i>)-3′′′,4′′′-Dimethoxystyryl] Cyclohex-1-ene, Exhibits Apoptogenic Properties in T-Acute Lymphoblastic Leukemia Cells via Induction of p53-Independent Mitochondrial Signalling Pathway 

Figure 4 | A Phenylbutenoid Dimer, cis-3-(3′,4′-Dimethoxyphenyl)-4-[(E)-3′′′,4′′′-Dimethoxystyryl] Cyclohex-1-ene, Exhibits Apoptogenic Properties in T-Acute Lymphoblastic Leukemia Cells via Induction of p53-Independent Mitochondrial Signalling Pathway 