Eupomatenoid-5 Isolated from Leaves of Piper regnellii Induces Apoptosis in Leishmania amazonensis
Figure 3
Mitochondrial production in promastigote forms of L. amazonensis treated with eupomatenoid-5 at 30.0, 85.0, and 170.0 M for up to 4 h using the fluorescence probe MitoSOX. At the indicated times, parasites were used to fluorometrically measure oxidized MitoSOX (oxMitoSOX). The data are expressed as the mean fluorescence (in arbitrary units) ± SD of at least three independent experiments. *, significant difference compared with the control group (i.e., untreated parasites).
