Research Article
Release of Propolis Phenolic Acids from Semisolid Formulations and Their Penetration into the Human Skin In Vitro
Table 1
The composition of semisolid propolis preparations after optimization.
| | Excipient | Ointment
(%) | W/O cream
(%) | Hydrogel
(%) |
| | Vaseline, white | 68.4 | — | — | | Lanolin, anhydrous | 13.6 | — | — | | Glycerol | 15 | — | — | | Soft propolis extract | 3 | 3 | — | | Pionier PLW | — | 50 | — | | Span 80 | — | 7 | — | | Purified water | — | 40 | 8.5 | | Poloxamer 407 | — | — | 20 | | Sodium carboxymethylcellulose | — | — | 1.5 | | Aqueous propolis extract | — | — | 70 |
| | Dynamic viscosity (Pa · s) | | | |
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