Long-Term Regeneration and Functional Recovery of a 15 mm Critical Nerve Gap Bridged by Tremella fuciformis Polysaccharide-Immobilized Polylactide Conduits
Histology for the nerve sections at the midconduit of PLA and PLA/TF conduits (15 mm gap) after 4, 6, and 8 months of implantation. (a) Images at low magnification showed the contour and shape of the regenerated tissue. (b) Images at higher magnification showed myelins and more detailed morphology. Blood vessel (V), myelin (M), fat tissue (F), and regenerated nerve (RN). Scar bars in (a) represent 100 μm, and those in (b) represent 200 μm. Dotted boxes in (b) indicate the formation of self-organized bundles.
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