Dissection of Mechanisms of a Chinese Medicinal Formula: Danhong Injection Therapy for Myocardial Ischemia/Reperfusion Injury In Vivo and In Vitro

Figure 6

Effects of pretreatment with A, B, C, and DHI on the levels of NF-κB (a), Nrf2 (b), and Caspase-3 (c) in neonatal rat cardiomyocytes subjected to SI/R. SI/R, simulated ischemia/reperfusion; A, hydroxysafflor yellow A; B, salvianolic acid B; C, Danshensu; DHI, Danhong injection; W, wortmannin; U, U0126. Data are presented as mean ± SD of at least 3 independent experiments. ^##𝑃<0.01 versus control; *𝑃<0.05, **𝑃<0.01 versus SI/R.

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