Activation of AMP-Activated Protein Kinase and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells
(a) Cells were treated with CB-PIC (0 or 40 g/mL) under normoxia and hypoxia both for 6 and 8 hr. Cell cycle distribution was analyzed by flow cytometry. (b) Bar graphs represent the percentage of the sub-G1 of apoptotic DNA fraction. Data are presented as means SD. compared with normoxia CB-PIC-(40 g/mL) treated groups.