Effects of Acupuncture on 1-Chloro-2,4-dinitrochlorobenzene-Induced Atopic Dermatitis

Figure 3

Effects of acupuncture treatment on production of cytokines. IL-4, IL-8, TNF-α, and IL-1β mRNA expression was increased significantly by DNCB sensitization. MP treatment significantly reduced IL-4, IL-8, and TNF-α expression. NOR: mice treated with vehicle; DNCB: mice sensitized with DNCB; LP: mice sensitized with DNCB and treated at local points around the lesion; MP: mice sensitized with DNCB and treated at meridian point LI11. ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001, compared to the NOR group; ^##𝑃<0.01, ^###𝑃<0.001, compared to the DNCB group; ^§§𝑃<0.01, ^§§§𝑃<0.001, compared to the LP group. One-way ANOVA followed by the Newman-Keuls test was performed for statistical analysis, and all data are presented as the mean ± S.D.