Research Article

Effects of the Chinese Traditional Prescription Xiaoyaosan Decoction on Chronic Immobilization Stress-Induced Changes in Behavior and Ultrastructure in Rat Hippocampus

Figure 3

Ultrastructural changes of the hippocampus CA1 subregion in control (A), sham-operated (B), CIS (C), XYS (D), and CNQX (E) groups, respectively. (a) The morphology and structure of hippocampal pyramidal cells, including the nucleus and most of the organelles. Mitochondria, rough endoplasmic reticulum, Golgi’s body, and free ribosome can be identified near the nucleus. A curly nucleus (C) and several cytolysosomes (triangle, (a)(C)) in the cytolymph are shown in CIS-induced hippocampus. (b) Synapses in hippocampus CA1. The synaptic structure is not clear and the fusion of pre- and postsynaptic membranes is visible in CIS-induced hippocampus (arrowheads, (b)(C)).
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