Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 3

Research Article

Tualang Honey Promotes Apoptotic Cell Death Induced by Tamoxifen in Breast Cancer Cell Lines

Figure 3

Effect of TH, TAM, and TH + TAM on the mitochondrial membrane potential of MCF-7 cells. Cells treated with TH alone or in combination with TH (5 μM) for 24 h were stained with mitochondrial-selective JC-1 dye and analyzed by flow cytometry. (a) The dot plots represent the population of mitochondrial membrane-depolarized cells on the lower right (LR) and mitochondrial membrane-polarized cells on the upper right (UR). (b) Bar graphs represent the percentages of polarized and depolarized cells. Data are expressed as mean ± standard deviation from three independent experiments. significantly different from untreated control. significantly different from TAM alone.