Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 4

Research Article

Tualang Honey Promotes Apoptotic Cell Death Induced by Tamoxifen in Breast Cancer Cell Lines

Figure 4

Effect of TH, TAM, and TH + TAM on the mitochondrial membrane potential of MDA-MB-231 cells. Cells treated with TH alone or in combination with TH for 24 h were stained with mitochondrial-selective JC-1 dye and analyzed by flow cytometry. (a) The dot plots represent the population of mitochondrial membrane-depolarized cells on the lower right (LR) and mitochondrial membrane-polarized cells on the upper right (UR). (b) Bar graphs represen the percentages of polarized and depolarized cells. Data are expressed as mean ± standard deviation from three independent experiments. significantly different from untreated control.