Research Article

An fMRI Study of Neuronal Specificity in Acupuncture: The Multiacupoint Siguan and Its Sham Point

Table 1

Brain regions activated by acupuncture stimulation at the real acupoint (Siguan) (compared with the resting-state).

Brain areasBASideCluster sizeTalairach-value

Calcarine gyrusL419−1.5−67.520.55.54
Middle occipital gyrus*R8534.5−61.529.55.39
Middle occipital gyrus19L21−28.5−82.520.54.53
Middle temporal gyrusR4246.5−70.55.54.55
22L79−49.5−58.514.54.29
Inferior temporal gyrusL39−43.5−19.5−15.54.19
Inferior frontal gyrusL74−40.522.5−6.54.77
Superior medial prefrontal gyrus10L29−4.558.52.54.26
Anterior cingulate cortex10R174.549.58.53.35
Postcentral gyrusL21−28.5−31.547.54.06
Caudate nucleusL37−19.528.511.53.88
Cerebellum (crus 2)L41−31.5−67.5−33.54.34
R2822.5−79.5−27.54.47
Cerebellum (VIII)*R307.5−49.5−54.53.66

The peak voxel for each cluster and the corresponding name of the anatomical region are given. Asterisks indicate peak voxels located in the white matter. In these cases, we labeled the brain region in which most voxels in the cluster were located.
BA: Brodmann area. (AlphaSim correction).