Protective Effect of Danhong Injection on Acute Hepatic Failure Induced by Lipopolysaccharide and D-Galactosamine in Mice
Figure 4
Effects of DHI on apoptosis of hepatocytes. TUNEL assay of apoptotic hepatocytes in the liver was performed 6 h after D-GalN/LPS injection with or without DHI. DHI (1.5, 3, and 6 mL/kg body weight) or sterile PBS was intraperitoneally administrated at 12 and 1 h before D-GalN/LPS injection (original magnification, 400x). (a) Control group, (b) D-GalN/LPS-stimulated group, (c) NAC-treated group, (d) DHI (6 mL/kg) + D-GalN/LPS-stimulated group, (e) DHI (3 mL/kg) + D-GalN/LPS-stimulated group, and (f) DHI + D-GalN/LPS-stimulated (1.5 mL/kg) group.
