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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 163036, 11 pages
http://dx.doi.org/10.1155/2014/163036
Review Article

Chinese Herbal Medicine on Dyslipidemia: Progress and Perspective

Ming Guo,1,2 Yue Liu,1,2 Zhu-Ye Gao,1,2 and Da-zhuo Shi1,2

1Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China
2China Heart Institute of Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100091, China

Received 1 December 2013; Accepted 6 January 2014; Published 13 February 2014

Academic Editor: Waris Qidwai

Copyright © 2014 Ming Guo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Dyslipidemia is an independent risk factor of cardiovascular diseases. The statins are a milestone in the primary and second prevention of cardiovascular diseases and significantly improved its prognosis. Along with the long-term treatment with statins in combination with other hypolipidemic drugs or alone, its safety has attracted a particular attention in clinic, such as the elevation of transaminase and rhabdomyolysis, which have raised an idea of developing the other types of lipid-lowering agents from botanic materials. Traditional Chinese medicine (TCM) has been used in clinical practice for more than 2000 years in China and showed some beneficial effects for human health and many diseases. Recently, many studies demonstrated a favorable effect of TCM for treating dyslipidemia; however, its mechanism remains unclear or totally unknown. The progress and perspective of studies on dyslipidemia with single Chinese herb and its monomers or effective extracts during the past 10 years are discussed in the present review.