Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 3

Research Article

Amelioration of Diabetes and Painful Diabetic Neuropathy by Punica granatum L. Extract and Its Spray Dried Biopolymeric Dispersions

Table 3

Subacute effect of Pg, F1, F2, and GA on body weights in alloxan-induced diabetic mice (n = 7).

GroupDose (mg/kg)Mean body weight ± SEM (gm)
1st day3rd day5th day8th day

Control25.90 ± 0.5026.00 ± 0.60 26.01 ± 0.97 26.62 ± 0.70
Diabetic controla28.68 ± 0.7027.10 ± 0.2027.15 ± 0.80 27.69 ± 0.50
GBb522.90 ± 0.7028.17 ± 1.70 28.54 ± 0.40 30.37 ± 1.10*
Pg b2524.11 ± 2.6027.70 ± 1.5030.20 ± 1.6030.40 ± 2.10**
Pg b5029.30 ± 1.9029.20 ± 1.6029.30 ± 1.8031.50 ± 2.20**
Pg b10030.24 ± 2.6030.40 ± 1.7031.54 ± 3.9031.98 ± 2.90*
Placebo F120027.50 ± 2.1027.50 ± 2.2027.00 ± 2.4026.88 ± 2.50
F1b5031.11 ± 1.2031.00 ± 1.5031.10 ± 1.6031.50 ± 1.90
F1b10030.10 ± 1.4029.50 ± 2.5030.50 ± 2.4031.70 ± 2.50*
F1b20031.00 ± 1.9029.00 ± 3.5032.60 ± 2.9033.80 ± 2.80*
Placebo F220024.50 ± 2.5024.45 ± 2.6024.01 ± 2.5023.60 ± 2.40
F2b5027.30 ± 1.9027.40 ± 1.8027.5 ± 1.9027.8 ± 2.00
F2b10028.40 ± 1.4028.5 ± 1.5028.90 ± 1.6030.25 ± 2.50*
F2b20031.90 ± 1.9032.00 ± 1.8032.50 ± 1.9033.11 ± 2.10*
GAb329.20 ± 1.2030.30 ± 1.3030.50 ± 1.1032.05 ± 1.20*
GAb631.56 ± 1.1032.67 ± 0.6033.45 ± 1.0034.10 ± 1.60*
GAb1230.20 ± 1.2030.30 ± 1.3029.50 ± 1.5030.56 ± 1.40

SEM: standard error of the mean.
P < 0.05 significant from the control animals.
Compared to vehicle control.
Compared to diabetic control.

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