Akebia trifoliate (Thunb.) Koidz Seed Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cell Lines via Inducing Endoplasmic Reticulum Stress

Table 5

List of genes with significant expression in the KEGG-apoptosis pathway for HuH7 cells (fold change ≥1.5-fold).

Probe set ID	Gene symbol	Control	G418	ATSE	1/2(G418 + ATSE)	ATSE/control
8149733	TNFRSF10B	408	688	794	805	1.95
7966746	HRK	153	188	252	403	1.65
8065569	BCL2L1	1172	1558	1822	1293	1.55
8012257	TP53	212	209	320	66	1.51
7956989	MDM2	766	1242	1138	680	1.50
7924733	PARP1	102	90	67	56	−1.50

G418 (0.45 mg/mL); ATSE: Akebia trifoliate seed extract (0.625 mg/mL); 1/2(G418 + ATSE): a combination of half dose of each accordingly.