Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study

Table 2

Numbers of patients who were exposed to different mistletoe preparations and adverse drug reactions that occurred.

Preparation	Patients	ADRs*	Relative frequency of ADRs (%)^#	Types of ADRs
Abnoba viscum (n.s.)	2
Abnoba viscum Abietis	15
Abnoba viscum Aceris	2
Abnoba viscum Amygdali	2
Abnoba viscum Crataegi	1
Abnoba viscum Fraxini	133	7 (10)	5.3	Local reaction × 2, pruritus × 2, urticaria × 2, pyrexia, myalgia, hypoaesthesia oral, paraesthesia
Abnoba viscum Mali	2
Abnoba viscum Pini	4
Abnoba viscum Quercus	7	1 (1)	14.3	Rash
Total Abnoba viscum	161	8 (11)	5.0
Helixor (n.s.)	5	0
Helixor Abietis	106	2 (2)	2.8	Urticaria, pruritus
Helixor Mali	187	8 (12)	4.3	Pyrexia × 5, pruritus × 2, fatigue, infusion site inflammation, headache, hypersensitivity × 2
Helixor Pini	51
Total Helixor	321	10 (15)	3.1
Iscador (n.s.)	4
Iscador Mali	8	1 (2)	12.5	Pyrexia × 2
Iscador Mali c. Arg.	1
Iscador Mali special	8	2 (3)	25.0	Pyrexia, vomiting, chills
Iscador Pini	2
Iscador Quercus	9	1 (1)	11.1	Pyrexia
Iscador Quercus special	8
Iscador Ulmi c. Hg	2
Total Iscador	40	4 (6)	10.0
Total	475	22	4.6

∗Number of patients to have an ADR followed by the total number of ADRs in brackets.
^#Percentage of patients exposed to that preparation type who had an ADR.
n.s.: not specified.