Inhibitory and Acceleratory Effects of Inonotus obliquus on Tyrosinase Activity and Melanin Formation in B16 Melanoma Cells
Figure 8
(a) Inhibitory effects of Fa-b on tyrosinase activity in B16 melanoma cells. Lineweaver-Burk plots in the absence (control) or in the presence of Fa-b with L-DOPA as the substrate are shown. Concentrations of Fa-b for the curve 1–5 at 0, 25, 50, 100, and 180 μM, respectively. (b) The plot of slope versus the concentration of Fa-b for determining the inhibition constants . (c) The plot of intercept versus the concentration of Fa-b for determining the inhibition constants .
