Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2014 (2014), Article ID 294103, 5 pages
Research Article

The Effect of Scalp Point Cluster-Needling on Learning and Memory Function and Neurotransmitter Levels in Rats with Vascular Dementia

1Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, China
2Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and TCM Research Center Graz, Medical University of Graz, 8036 Graz, Austria
3Privatclinic Lassnitzhoehe, 8301 Lassnitzhoehe, Austria

Received 26 April 2014; Revised 1 June 2014; Accepted 2 June 2014; Published 15 June 2014

Academic Editor: Yi-Hung Chen

Copyright © 2014 Junli Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We observed the effect of scalp point cluster-needling treatment on learning and memory function and neurotransmitter levels in rats with vascular dementia (VD). Permanent ligation of the bilateral carotid arteries was used to create the VD rat model. A Morris water maze was used to measure the rats’ learning and memory function, and the changes in neurotransmitter levels in the rats’ hippocampus were analyzed. The results show that scalp point cluster-needling can increase the VD rat model’s learning and memory score. The VD rat model’s learning and memory score was significantly different when compared with that of the sham operation group . Hippocampal acetylcholine (ACh), dopamine (DA), and 5-hydroxytryptamine (5-HT) concentrations significantly decreased in the rat model. Compared with the model group, the scalp point cluster-needling group’s ACh concentration markedly increased and DA and 5-HT levels increased as well. In conclusion, scalp point cluster-needling can improve learning and memory function in VD rats, and its function may be related to an increase in neurotransmitter release.