Review Article

Efficacy of Acupuncture for Psychological Symptoms Associated with Opioid Addiction: A Systematic Review and Meta-Analysis

Table 1

Summary of studies included in the review.

Author
(year)
Number of subjects
(Acu/Control)
Inclusion criteriaIntervention typeType of control groupStudy durationFollow-up periodsOutcome measureResults reportedJadad scoreDatabase

Lua and Talib 2013 [40] 97
(55/42)
Dependence on opiatesAAMMTTwo monthsNo Craving Better than AA
3PubMed
English Language Journal

Bearn et al.
2009 [41]
82
(41/41)
DSM-IVAAPlaceboFour weeksNoMCSNS3PubMed
English Language Journal

Avants et al.
2000 [42]
82
(28/27/27)
DSM-IV-R AAShamEight weeksNoASI
SOCRATES version TCS
NS4PubMed
English Language Journal

Meade et al.
2010 [43]
55
(26/29)
Diagnosis of opioid dependenceTEASShamFour daysNoCravingNS 4PubMed
English Language Journal

Wu et al.
2003 [44]
120
(30/30/30/30)
CCMD-II-R
DSM-III-R
Body acupuncture
HAN’s
BuprenorphineTen daysNoCraving Acu with opioid more better
1PubMed
Chinese Language Journal

Song et al.
2012 [45]
62
(35/27)
DSM-III-RBody acupunctureNo treatmentEight weeksNoAnxiety scoresNSD2PubMed
Chinese Language Journal

Zeng et al.
2005 [46]
57
(31/26)
DSM-III-RBody acupunctureMMTTen daysNoAnxietyBetter than control
1PubMed
Chinese Language Journal

Mu et al.
2010 [47]
120
(30/30/30/30)
DSM-IVElectro acupuncturePlacebo
No treatment
Ten weekssix monthsCraving scores of VASBetter than control
2PubMed
Chinese Language Journal

Zhang et al.
2000 [48]
181
(121/60)
DSM-III-R HANSPlaceboTwo weeksNo Craving
Anxiety
Better than control
1PubMed
Chinese Language Journal

Yang et al.
2007 [49]
40
(20/20)
DSM-IV-TRBody acupuncture
AA
Body acupunctureFour weeksNo AnxietyBetter than acu control
2CNKI
Chinese Language Journal

Hou et al.
2009 [50]
60
(30/30)
ICD-10Body acupunctureNo treatmentThree weeksNo Depression Better than control
2CNKI
Chinese Language Journal

Wen et al.
2005 [51]
220
(111/109)
DSW-IVBody acupunctureDrugTen daysNo AnxietyBetter than control
2CNKI
Chinese Language Journal

Zhan [52]81
(34/47)
DSM-IV-TRScalp acupunctureMethadoneOne monthsNoCraving scoreBetter than control
3CNKI
Chinese Language Journal

Mu et al.
2008 [53]
120
(30/30/30)
DSM-IV electro acupunctureNo treatmentTen weeksNoAnxiety DepressionBoth Acu group better than control

2CNKI
Chinese Language Journal

Yang et al.
2011 [54]
128
(65/63)
DSM-III-RBody acupuncture DrugDrugTwelve days NoAnxietySame as the drug group
2CNKI
Chinese Language Journal

Rong et al.
2006 [55]
94
(33/31/30)
DSM-IV Scalp and electro acupunctureBody acupuncture
Methadone
Ten daysNoAnxiety Better than control
3CNKI
Chinese Language Journal

NS: not significant; AA: auricular acupuncture; HANS: Han’s acupoint nerve stimulator; CCMD: Chinese Classification of Mental Disorders; DSM: The Diagnostic and Statistical Manual of Mental Disorders; VAS: visual analogue scale; ASI: Addiction severity Index; SOCRATES: the stage of Change Readiness and Treatment Eagerness Scale; TCS: Treatment Credibility Scale; MCS: the Maudsley Craving Scale; SOWS: Severity of Opiate Withdrawal Symptom Scale; NADA: National Acupuncture Detoxification Association; TEAS: transcutaneous electric acupoint stimulation; NSD: no statistical difference.