TY - JOUR A2 - Kong, Jian AU - Hsu, Wing-sze AU - Shen, Xiao-yu AU - Yang, Jia-min AU - Luo, Li AU - Zhang, Ling AU - Qi, Dan-dan AU - Shen, Song-xi AU - Zhu, Shi-peng AU - Zhao, Ya-fang AU - Ren, Xiao-xuan AU - Guo, Meng-wei AU - Li, Xiao-hong AU - Ji, Bo AU - Zhang, Lu-fen AU - Zhu, Jiang PY - 2014 DA - 2014/04/09 TI - Effects of Acupuncture Applied to Sanyinjiao with Different Stimuli on Uterine Contraction and Microcirculation in Rats with Dysmenorrhea of Cold Coagulation Syndrome SP - 328657 VL - 2014 AB - In this study, we try to evaluate the effects of acupuncture stimulation with different amounts at Sanyinjiao (SP6) on uterine contraction and uterus microcirculation in rats with dysmenorrhea of cold coagulation syndrome and to explore whether there is direct relativity between “De qi” and needle stimulus intensity. Diestrus female rats were randomly divided into 4 groups, including saline control group, model control group, “A” stimulus group (with strong stimulus), and “B” stimulus group (with weak stimulus). We found that dysmenorrhea rats of the cold coagulation syndrome present a high intensity in uterine tension and high contraction of microvascular diameter. Acupuncture applied with two different stimuli could relieve the symptoms, but, compared with “B” stimulus, “A” stimulus leads to better outcomes on reducing uterine contraction and increasing diameter of uterine microvascular; moreover, hand manipulation during needling mediates the curative effect on the microvascular diameter. Our finding indicates that using thick needles and deep insertion with hand manipulation are more effective and achieve desired level of “De qi” in dysmenorrhea rats. SN - 1741-427X UR - https://doi.org/10.1155/2014/328657 DO - 10.1155/2014/328657 JF - Evidence-Based Complementary and Alternative Medicine PB - Hindawi Publishing Corporation KW - ER -