Ethanolic Extract of Butea monosperma Leaves Elevate Blood Insulin Level in Type 2 Diabetic Rats, Stimulate Insulin Secretion in Isolated Rat Islets, and Enhance Hepatic Glycogen Formation
Figure 8
Effects of ethanol extract of Butea monosperma (BM) on (a) intestinal disaccharidase activity and (b) gastrointestinal motility (by BaSO4 traversed) in type 2 diabetic rats. Rats were fasted for 20 h before the oral administration of ethanol extract of BM (250 mg/kg, 500 mg/kg, and 1000 mg/kg body weight). Enzyme activity was determined and BaSO4 was administered at 60 min. Motility was measured over the following 15 min. Acarbose (200 mg/Kg) and Loperamide (LPM) 5 mg/Kg) and Domperidone (DMP) (10 mg/Kg) were used as reference controls for disaccharidase activity test and gastrointestinal motility test respectively. Values are means and standard deviations represented by vertical bars (). Mean values marked with an asterisk (*) were significantly different from those of diabetic control rats () (derived from repeated measures ANOVA and adjusted using Bonferroni correction).
