Subacute Oral Toxicity of Yukmijiwhang-Tang in Crl:CD Sprague-Dawley Rats and Its Cytotoxicity

Figure 1

Three-dimensional chromatogram of YMJ by HPLC-PDA. Column: Gemini C₁₈ (250 × 4.6 mm, 5 μm); mobile phase: 1.0% (v/v) acetic acid in water (A) and 1.0% (v/v) acetic acid in acetonitrile (B) (5–40% B for 0–30 min, 40–100% B for 30–40 min, 100% B for 40–45 min, and 100–5% B for 50 min); flow rate: 1.0 mL/min; retention time: 5.95 min (gallic acid), 8.09 min (5-HMF), 13.14 min (morroniside), 16.15 min (loganin), 18.30 min (paeoniflorin), and 36.00 min (paeonol).