Evaluation of a Crataegus-Based Multiherb Formula for Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Table 3

Changes in body weight, lipids, and glucose at week 12.

	Placebo (𝑛=20)			Herb formula (𝑛=20)			𝑃 value; (versus placebo)
	Baseline	Week 12	% change	Baseline	Week 12	% change
Body weight, kg	71.3±17.2	69.0±20.9	−2.7±15.0	65.0±10.7	65.7±10.0	0.8±1.9	0.310
TC, mmol/L	5.39±0.89	5.61±1.01	4.5±10.3	5.90±1.17	5.96±1.21	1.4±10.5	0.362
HDL-C, mmol/L	1.29±0.39	1.34±0.46	0.7±12.4	1.28±0.25	1.27±0.30	2.0±12.4	0.276
TG, mmol/L	2.35±1.18	2.21±1.04	−6.7 (−18.3, 15.8)	2.00±0.71	2.42±1.61	5.8 (−14.8, 16.3)	0.383
LDL-C, mmol/L	3.04±0.82	3.27±0.95^∗	7.4±15.5	3.72±1.17	3.64±1.17	−2.0±13.6	0.049
Non-HDL-C, mmol/L	4.10±0.68	4.28±0.78	3.6±9.2	4.63±1.13	4.69±1.16	0.4±12.5	0.368
Fasting glucose, mmol/L	5.57±1.23	5.80±2.02	2.9±12.1	5.84±2.17	5.80±1.19	0.3±7.8	0.432
HbA1c, %	6.57±0.98	6.54±1.36	−1.1±5.7	6.59±0.83	6.31±0.65^∗∗	−3.9±4.9	0.098

TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides.
Data are presented as mean ± SD or median (interquartile range).
^∗𝑃<0.05; ^∗∗𝑃<0.01 compared to baseline.