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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 381649, 6 pages
http://dx.doi.org/10.1155/2014/381649
Research Article

Long-Term Treatment with Aqueous Garlic and/or Tomato Suspensions Decreases Ehrlich Ascites Tumors

1Environmental and Experimental Pathology Post-Graduation, Paulista University (UNIP), Rua José Maria Whitaker 290, 05622-001 São Paulo, SP, Brazil
2Pharmacology Department, Federal University of São Paulo (UNIFESP), Rua Sena Madureira, 04021-001 São Paulo, SP, Brazil
3Veterinary Medicine, University Metodista of São Paulo, Rua Alfeu Tavares 149, 09641-000 São Bernardo do Campo, SP, Brazil

Received 23 February 2014; Revised 26 April 2014; Accepted 28 April 2014; Published 30 June 2014

Academic Editor: Khalid Rahman

Copyright © 2014 Jenifer Bom et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We evaluated the preventive and therapeutic effects of aqueous suspensions of garlic, tomato, and garlic + tomato in the development of experimental Ehrlich tumors in mice. The aqueous suspensions (2%) were administered over a short term for 30 days before tumor inoculation and 12 days afterward, and suspensions at 6% were administered for 180 days before inoculation and for 12 days afterward. The volume, number, and characteristics of the tumor cells and AgNOR counts were determined to compare the different treatments. Aqueous 6% suspensions of garlic, tomato, and garlic + tomato given over the long term significantly reduced tumor growth but when given over the short term, they did not alter tumor growth.