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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 381976, 10 pages
Research Article

Effects and Mechanism of Bufei Yishen Formula in a Rat Chronic Obstructive Pulmonary Disease Model

1Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China
2College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150086, China
3Respiratory Disease Institute, The First Affiliated Hospital of Henan University of TCM, Zhengzhou 450000, China
4Bioinformatics Centre, School of Life Science, University of Electronic Science and Technology of China, Chengdu 610054, China

Received 17 January 2014; Revised 16 April 2014; Accepted 18 April 2014; Published 14 May 2014

Academic Editor: Syed Ibrahim Rizvi

Copyright © 2014 Jiansheng Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1: DEGs between experimental groups. (A) DEGs between control and COPD groups. (B) DEGs between COPD and BYF groups.

Computational method of the DEGs: after microarray experiments, raw image data were converted to CEL and pivot files using Agilent Feature Extraction Software version All downstream microarray analyses were performed using Agilent GeneSpring GX software version 11.0. Microarray datasets were normalized in GeneSpring GX using the Agilent FE one-color scenario (mainly median normalization); Log 2-transformed data were normalized by quantile normalization and used for comparisons. Differentially expressed genes were identified through fold change (|log ratio|>1) and Student’s t-test screening (P < 0.05).

  1. Supplementary Table