Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti-Inflammatory Activity of the Main Flavonoid from Kalanchoe pinnata

Figure 3

Effect of KPFE (a) and KPFV (b) on the croton oil-induced mice ear edema. KPFE, KPFV, or dexamethasone (Dexa) was subcutaneously administrated 30 min before application of croton oil (2.5% in acetone, 20 μL) or acetone on the inner surface of the right and left ear, respectively. After four hours, the weight difference between the right and left ears was measured. , , and significantly different from the vehicle-treated group. Values represent the mean ± SEM of 10 mice.

(a)

(b)