Is It a New Approach for Treating Senile Hypertension with Kidney-Tonifying Chinese Herbal Formula? A Systematic Review of Randomized Controlled Trials

Table 1

Characteristics and methodological quality of included studies.

Study ID	Sample	Diagnosis standard	Intervention	Control	Course (week)	Outcome measure
Lu et al., 2007 [16]	90	JNC-7	KT formula plus indapamide	Placebo plus indapamide	24	BP; BL; adverse effects
Hu et al., 2001 [17]	84	CGPMHBP-1987	KT formula	Captopril	2	BP; BL
Huang et al., 2007 [18]	60	1999 WHO-ISH GMH	KT formula plus amlodipine basylate	Amlodipine basylate	2	BP; ET
Kong, 2003 [19]	60	1999 WHO-ISH GMH	KT formula plus plendil	Plendil	4	BP
Zhang and Li, 2006 [20]	136	1999 WHO-ISH GMH	KT pill plus cilazapril	Cilazapril	8	BP; ET; BUN; Cr
Zhang et al., 2008 [21]	97	CGPMHBP-2005	KT pill plus captopril	Captopril	8	BP; BUN; Cr

Abbreviations: KT: kidney-tonifying; WHO-ISH GMH, WHO-ISH guidelines for the management of hypertension; CGPMHBP: China Guidelines on Prevention and Management of High Blood Pressure; JNC-7: Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; BP: blood pressure; BL: blood lipid; ET: endothelin; BUN: blood urea nitrogen; Cr: creatinine.