Acupuncture Relieves the Excessive Excitation of Hypothalamic-Pituitary-Adrenal Cortex Axis Function and Correlates with the Regulatory Mechanism of GR, CRH, and ACTHR

Figure 4

Effect of acupuncture on CRH protein expression. In M group, CRH protein expression was increased obviously in the hippocampus, PVN, and pituitary gland, which was significantly different as compared with N group. In MEA and MNEA groups, CRH protein expression was downregulated in hippocampus, PVN, and pituitary gland to different extents as compared with M group, but the results in MEA group were superior to MNEA group. The protein expression was increased significantly in the hippocampus and PVN in NEA group, which was different significantly as compared with N group. *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001 (𝑛=10--12) (#10944-1-AP, Datashect, 36KD, dilution: 1 : 500).