Acupuncture Relieves the Excessive Excitation of Hypothalamic-Pituitary-Adrenal Cortex Axis Function and Correlates with the Regulatory Mechanism of GR, CRH, and ACTHR

Figure 5

Effect of acupuncture on ACTHR protein expression. ACTHR protein expression was increased obviously in the pituitary gland and adrenal cortex in M group as compared with N group. ACTHR protein expression was downregulated in the pituitary gland and adrenal cortex in MEA and MNEA groups to different extents as compared with M group, but the results in MEA group were superior to MNEA group. The difference was not significant in comparison between NEA and N groups. *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001 (𝑛=10--12) (#H-70, Santa Cruz, 33KD, dilution: 1 : 1000).