Research Article

Analgesia Synergism of Essential Oil from Pericarp of Zanthoxylum schinifolium and Verapamil

Table 5

Effect of amplitude of action potential (AP) of sciatic nerve in toads ( , ).

GroupDosage (g/mL)Preadmin/mVProadmin/mVTime of AP
vanishing
1 min5 min10 minmin

RS4.35 ± 1.254.26 ± 1.324.30 ± 1.164.33 ± 1.53exist
EOZ0.2%4.39 ± 1.43 3.21 ± 0.85①③004.98 ± 0.92③
Ver0.05%4.42 ± 1.024.39 ± 1.324.43 ± 1.064.29 ± 1.34exist
EOZ + Ver0.2% + 0.05%4.45 ± 1.032.36 ± 1.02②③002.62 ± 0.58③⑤
Lid1%4.53 ± 1.124.52 ± 1.354.50 ± 1.65①③4.38 ± 1.65①③22.89 ± 6.52③

Compared with preadministration: ①: , ②: ; compared with NS group: ③: , ④: ; compared with EOZ group: ⑤: .