Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 1 / Review Article
Beneficial Effects of Rikkunshito, a Japanese Kampo Medicine, on Gastrointestinal Dysfunction and Anorexia in Combination with Western Drug: A Systematic Review Table 1 Administration of rikkunshito in combination with Western drugs in human studies.
Reference Western drugs Patients Outcome [4 ] Docetaxel/5-FU/cisplatin Esophageal cancer Improved QOL [5 ] S-1/cisplatin Unresectable or relapsed gastric cancer Improved anorexia [6 ] Gemcitabine Stage III/IV pancreatic cancer with ascites Prolonged median survival [7 ] Rabeprazole PPI-refractory GERD Improved GERD score [8 ] Lansoprazole PPI-refractory LPR Improved global sensation VAS scores [9 ] Rabeprazole Gastrointestinal symptoms after ESD Improved GSRS score [10 ] Fluvoxamine Depressive disorder Improved GSRS scores [11 ] Antidepressants or antipsychotics Elderly patients with dementia Increase in food intake [12 ] Anti-Parkinson drugs Parkinson's disease Ameliorated gastroparesis [13 ] Ofloxacin Healthy volunteers No effects on bioavailability [14 ] Levofloxacin Healthy volunteers No effects on bioavailability
ESD: endoscopic submucosal dissection; GERD: gastroesophageal reflux disease; LPR: laryngopharyngeal reflux; PPI: proton-pump inhibitor; QOL: quality of life; GSRS: Gastrointestinal Symptom Rating Scale; VAS: visual analog scale.
