Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 1

Research Article

A Platform for Screening Potential Anticholinesterase Fractions and Components Obtained from Anemarrhena asphodeloides Bge for Treating Alzheimer’s Disease

Table 1

The effects of the tested extracts on AChE and BuChE inhibitory activities.

SolventsAChE inhibition (%)BuChE inhibition (%)
Ultrasonic methodHeat reflux methodCold soak methodUltrasonic methodHeat reflux methodCold soak method

Petroleum ether1.6 ± 0.1
Dichloromethane41.5 ± 0.515.7 ± 0.741.2 ± 0.6
Ethyl acetate44.1 ± 0.527.7 ± 0.440.8 ± 0.8
Acetone38.8 ± 0.322.2 ± 0.337.9 ± 0.7
Methanol12.3 ± 0.45.4 ± 0.27.1 ± 0.3
95% ethanol4.9 ± 0.22.8 ± 0.13.9 ± 0.3
70% ethanol1.8 ± 0.11.6 ± 0.2
50% ethanol2.8 ± 0.10.5 ± 0.1
30% ethanol2.4 ± 0.11.8 ± 0.2
Water

AChE inhibition ratio of donepezil: 98.0 ± 0.5; BuChE inhibition ratio of donepezil: 80.2 ± 0.6.