Deer Antler Extract Improves Fatigue Effect through Altering the Expression of Genes Related to Muscle Strength in Skeletal Muscle of Mice

Table 3

The expressed genes that were up- or downregulated in the skeletal muscle of FSDTAE-treated group compared with the vehicle group.

Function	Symbol	Gene description	Fold change
Muscular system	Myom3	Mus musculus myomesin family, member 3	4.25
	Csrp2	Cysteine and glycine-rich protein 2	2.47
	Tnni1	troponin I, skeletal, slow 1	2.38
	Tnnt1	troponin T1, skeletal, slow	2.29
	Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	2.21
	Tpm2	tropomyosin 2, beta	2.17
	Actc1	actin, alpha, cardiac muscle 1	−2.06
	Crip2	Cysteine-rich protein 2	−2.32
	HSC70^a	Heat shock protein 8	−2.82
	Pln	Phospholamban	−2.83
	Tnni3	troponin I, cardiac 3	−4.85
	Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	−7.13
Nervous system development and function	Vps13a	vacuolar protein sorting 13A (chorein)	15.30
Energy metabolism	Car3	Carbonic anhydrase 3	2.14
	Car3	Carbonic anhydrase 3	2.08
Epithelial development and differentiation	Krt10	Keratin, type I cytoskeletal 10	2.75
	Krt10	Keratin, type I cytoskeletal 10	2.35
	Sbsn	suprabasin isoform 1	2.02
Cellular growth and proliferation	Pwp2	Periodic tryptophan protein 2 homolog	5.15
	Rarres2	Retinoic acid receptor responder 2	2.58
	CRBP-II	Cellular retinoic acid-binding protein-II	−2.07
	Spry2	Sprouty homolog 2 (Drosophila)	−3.58
Immune response	C3	Complement component 3	4.07
	C2	Complement component 2	2.45
Miscellaneous genes	Rnu22	Mus musculus small nucleolar RNA	21.85
	Targ3	transforming growth factor alpha regulated gene 3	12.53
	TSEG-2	testis-specific expressed protein 2	12.14
	Tmem165	Transmembrane protein 165	3.54
	Hoxc6	Homeo box C6	3.06
	Eras	ES cell-expressed Ras	2.9
	Olfr1018	Olfactory receptor 1018	2.9
	Serpina1a	Serine peptidase inhibitor, clade A, member 1a	2.34
	Rbp2	Retinol binding protein 2, cellular	−2.07
	Ptgds	Prostaglandin D2 synthase (brain)	−2.11
	Atxn7	ataxin 7	−2.41
	Ube2ql1	ubiquitin-conjugating enzyme E2Q family-like 1	−2.41
	Ankrd13d	Ankyrin repeat domain-containing protein 13D	−2.94
	Magee1	Melanoma antigen, family E, 1	−4.97
	Paip2b	poly(A) binding protein interacting protein 2B	−24.46
Unknown function	D1Ertd622e	hypothetical protein LOC52392	9.87
	5430409L15Rik	RIKEN cDNA 5430409L15 gene	2.81
	1810006K21Rik	Mus musculus RIKEN cDNA 1810006K21 gene	2.3
	A330009N23Rik	RIKEN cDNA A330009N23 gene	−2.13
	Hddc2	HD domain-containing protein 2	−7.28
	A630083H20Rik	RIKEN cDNA A630083H20 gene	−10.18

aOther designation Hspa.