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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 543564, 9 pages
Research Article

Potent Stimulation of Blood Flow in Fingers of Volunteers after Local Short-Term Treatment with Low-Frequency Magnetic Fields from a Novel Device

1Institute for Anatomy, Medical Faculty, Dresden University of Technology, Fiedlerstraße 42, 01307 Dresden, Germany
2Medical Clinic/Cardiology, Department of Molecular Cardiology, Medical Faculty, Dresden University of Technology, Fiedlerstraße 42, 01307 Dresden, Germany
3Institute for Biological Interfaces, Research Centre Karlsruhe, Kaiserstraße 12, 76131 Karlsruhe, Germany

Received 29 November 2013; Revised 27 February 2014; Accepted 10 March 2014; Published 21 May 2014

Academic Editor: Jen-Hwey Chiu

Copyright © 2014 Richard H. W. Funk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A novel hand-held low-frequency magnetic stimulator (MagCell-SR) was tested for its ability to stimulate microcirculation in fingers of healthy volunteers. Blood flow during and after 5 minutes exposure was quantified using Laser Doppler Perfusion Imaging Technique. The device was positioned between the wrist and the dorsal part of the backhand. Because the increase in blood flow could be caused by a release of nitric oxide (NO) from the vascular endothelial cells we tested NO production with a fluorescence marker and quantified the measurements in cell cultures of human umbilical endothelial cells (HUVEC). Exposure increased blood flow significantly, persisted several minutes, and then disappeared gradually. In order to assess the effect of a static magnetic field, the measurements were also carried out with the device shutoff. Here, only a small increase in blood flow was noted. The application of the rotating MagCell-SR to the HUVEC cultures leads to a rapid onset and a significant increase of NO release after 15 minutes. Thus, frequencies between 4 and 12 Hz supplied by the device improve microcirculation significantly. Therefore, this device can be used in all clinical situations where an improvement of the microcirculation is useful like in chronic wound healing deficits.