Myrcia bella Leaf Extract Presents Hypoglycemic Activity via PI3k/Akt Insulin Signaling Pathway

Table 2

Biochemical parameters and glycogen levels of control and diabetic mice treated during 14 days with saline or crude extract of M. bella (600 mg/Kg).

Parameters	CTL SAL	CTL EXT	STZ SAL	STZ EXT
Triglycerides (mg/dL)	105.1±12.5	79±17.88^@	139.4±12.6^@&	70.2±8.18^@∗
Total cholesterol (mg/dL)	142.9±12	83.6±14.8^@	190±13.8^@&	88.5±11.3^@∗
Total protein (mg/dL)	4.89±1.37	3.9±0.94	2.7±0.47	3.59±0.37
Basal insulin (ng/mL)	0.19±0.02	0.19±0.01	0.11±0.005^@&	0.13±0.01^@&
Hepatic glycogen (mg%)	0.33±0.07	0.33±0.05	0.11±0.03^@&	0.28±0.06^∗
Muscular glycogen (mg%)	0.21±0.01	0.21±0.02	0.15±0.01^@&	0.17±0.01^@&

CTL SAL (control mice treated with saline), CTL EXT (control mice treated with M. bella extract), STZ SAL (diabetic mice treated with saline), and STZ EXT (diabetic mice treated with M. bella extract). Values ​​are expressed as Means ± SEM. * versus STZ SAL, ^@ versus CTL SAL, ^& versus CTL EXT, 𝑛=8, 𝑃<0.05. ANOVA followed by Tukey’s posttest.