Research Article

Transcutaneous Neuromodulation at Posterior Tibial Nerve and ST36 for Chronic Constipation

Table 1

Anorectal motility and sensation profiles before and after TN/sham-TN treatment.

BaselineAfter 2-week TNAfter 2-week sham-TN

RAIR41.43 ± 5.9420 ± 4.36*34.29 ± 4.81**
Anal rest pressure (mmHg)69 ± 1.8374.84 ± 7.4275.93 ± 8.59
Maximal squeeze pressure (mmHg)153.14 ± 24.42170.56 ± 22.30150.3 ± 12.20
Duration of anal contraction (s)12.97 ± 0.4212.63 ± 0.5512.8 ± 0.59
First sensation (mL)40 ± 7.5624.29 ± 4.29*41.43 ± 7.05**
Desire of defecation (mL)75.71 ± 9.9760 ± 9.2685.71 ± 11.52
Urge of defecation (mL)137.14 ± 17.42114.29 ± 8.12148.57 ± 12.99
Maximum tolerable volume (mL)231.29 ± 19.12180 ± 9.00*222.86 ± 17.00**
Increase in rectal pressure (mmHg)39.37 ± 7.0133.94 ± 4.8936.94 ± 7.41
Paradoxical contraction (%)90.47 ± 9.5367.86 ± 17.8688.1 ± 7.89

< 0.05 versus baseline; < 0.05 versus sham-TN.