Antitumor Effects and Biological Mechanism of Action of the Aqueous Extract of the Camptotheca acuminata Fruit in Human Endometrial Carcinoma Cells
Figure 3
Effects of treatments using AE-CA or an equivalent concentration of CPT on cell-cycle arrest and the expression of cell-cycle protein markers in human endometrial carcinoma cells. (a) HEC-1A, (b) HEC-1B, and (c) KLE cells were treated using control medium, 0.2 mg/mL of AE-CA, or 0.16 μM CPT. The data are presented as the mean ± standard deviation (Student’s -test, ). (d) HEC-1A, HEC-1B, and KLE cells were treated using AE-CA (0.02 or 0.2 mg/mL) or CPT (0.16 μM) for 48 h, and the expression of cyclin-A2 and -B1 was examined using western blotting.
