Preclinical Safety of the Root Extract of Polygala tenuifolia Willdenow in Sprague-Dawley Rats and Beagle Dogs

Table 7

Food consumption of female rats.

Food consumption (g)
Study: 08-RR-011	Dose (mg/kg/day)				Sex: female
Weeks	0		360		600		1,000
	Mean ± S.D.		Mean ± S.D.		Mean ± S.D.		Mean ± S.D.
0	14.84 ± 0.52	10	14.34 ± 1.59	10	15.23 ± 0.64	10	13.08 ± 2.94	10
1	12.75 ± 1.17	10	13.01 ± 1.33	10	13.46 ± 1.36	10	12.51 ± 0.59	10
2	13.37 ± 0.85	10	12.28 ± 1.35	10	12.14 ± 1.33	10	11.84 ± 2.40	10
3	13.96 ± 0.45	10	13.95 ± 1.41	10	13.91 ± 1.06	10	12.10 ± 3.30	10
4	12.70 ± 1.82	10	12.74 ± 0.64	10	12.37 ± 1.31	10	11.52 ± 1.82	10
5	13.72 ± 1.89	10	14.14 ± 0.71	10	12.96 ± 2.60	10	12.35 ± 1.99	10
6	13.11 ± 1.21	10	13.40 ± 1.55	10	13.59 ± 1.38	10	11.43 ± 1.75	10
7	13.87 ± 0.87	10	12.68 ± 1.13	10	12.16 ± 0.51	10	11.07 ± 3.29	10
8	11.58 ± 1.08	10	12.81 ± 1.23	10	12.68 ± 1.33	10	12.75 ± 1.06	9
9	12.44 ± 1.24	10	13.19 ± 0.42	10	12.65 ± 1.72	10	11.69 ± 1.68	9
10	14.33 ± 1.06	10	13.49 ± 0.81	10	11.81 ± 2.21	10	12.42 ± 1.49	8
11	13.06 ± 1.28	10	12.76 ± 0.70	10	11.64 ± 1.12	10	12.41 ± 1.01	8
12	13.35 ± 0.65	10	13.10 ± 1.30	10	13.33 ± 2.25	10	13.15 ± 0.91	8
13	14.33 ± 1.19	10	14.44 ± 1.43	10	13.68 ± 2.47	10	15.49 ± 1.55	8