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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 580745, 11 pages
http://dx.doi.org/10.1155/2014/580745
Research Article

Chemical Profiling of an Antimigraine Herbal Preparation, Tianshu Capsule, Based on the Combination of HPLC, LC-DAD-MSn, and LC-DAD-ESI-IT-TOF/MS Analyses

1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
2National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Beijing 100700, China
3Jiangsu Kanion Pharmaceut Co. Ltd., Lianyungang 222001, China

Received 17 April 2014; Revised 28 June 2014; Accepted 30 June 2014; Published 20 July 2014

Academic Editor: Shi-Biao Wu

Copyright © 2014 Juanjuan Liang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Chinese Pharmacopoeia Commission, Chinese Pharmacopoeia, vol. 1, China Medical Science Press, Beijing, China, 2010.
  2. W. Xia, M. J. Zhu, Z. Zhang et al., “Effect of Tianshu capsule in treatment of migraine: a meta-analysis of randomized control trials,” Journal of Traditional Chinese Medicine, vol. 33, no. 1, pp. 9–14, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. L. Wang, J. M. Zhang, Y. L. Hong, Y. Feng, M. W. Chen, and Y. T. Wang, “Phytochemical and pharmacological review of Da Chuanxiong formula: a famous herb pair composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma for headache,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 425369, 16 pages, 2013. View at Publisher · View at Google Scholar
  4. S. M. Ni, D. W. Qian, E. X. Shang, J. A. Duan, J. M. Guo, and Y. P. Tang, “Analysis of Chemical composition of Da chuanxiong Fang by ultra performance liquid chromatography-electrospray ionization quadrupole time of flight/mass spectrometry,” Chinese Journal of Experimental Traditional Medical Formulae, vol. 16, no. 1, pp. 40–45, 2010. View at Google Scholar
  5. L. Shen, X. Lin, S. Liang et al., “Characterization on central ingredients of active components in dachuanxiong fang based on HPLC-DAD-MSn,” Chinese Journal of Experimental Traditional Medical Formulae, vol. 18, no. 7, pp. 128–134, 2012. View at Google Scholar
  6. Y. F. Wei, X. Lin, N. Zhang, and Y. Feng, “UPLC-MS analysis of constituents of Dachuanxiong Fang active parts absorbed into blood,” Zhongguo Zhongyao Zazhi, vol. 36, no. 9, pp. 1245–1248, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. Wei, N. Zhang, X. Lin, and Y. Feng, “Release characteristics in vitro and pharmacokinetics of Da Chuanxiong Fang multiunit drug delivery system in rats,” Acta Pharmaceutica Sinica, vol. 46, no. 9, pp. 1150–1155, 2011. View at Google Scholar · View at Scopus
  8. X. L. Zhang, L. F. Liu, L. Y. Zhu et al., “A high performance liquid chromatography fingerprinting and ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry chemical profiling approach to rapidly find characteristic chemical markers for quality evaluation of dispensing granules, a case study on Chuanxiong Rhizoma,” Journal of Pharmaceutical and Biomedical Analysis, vol. 88, pp. 391–400, 2014. View at Google Scholar
  9. X. Z. Zhang, H. B. Xiao, Q. Xu, X. L. Li, J. N. Wang, and X. M. Liang, “Characterization of phthalides in Ligusticum chuanxiong by liquid chromatographic-atmospheric pressure chemical ionization-mass spectrometry,” Journal of Chromatographic Science, vol. 41, no. 8, pp. 428–433, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Li, R. Yan, Y. Tam, and G. Lin, “Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong HORT. (Rhizoma Chuanxiong),” Chemical and Pharmaceutical Bulletin, vol. 55, no. 1, pp. 140–144, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Wang, H. B. Xiao, X. M. Liang, and L. Wei, “Identification of phenolics and nucleoside derivatives in Gastrodia elata by HPLC-UV-MS,” Journal of Separation Science, vol. 30, no. 10, pp. 1488–1495, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. T. Yi, K. S. Leung, G. H. Lu, and H. Zhang, “Comparative analysis of Ligusticum chuanxiong and related umbelliferous medicinal plants by high performance liquid chromatography-electrospray ionization mass spectrometry,” Planta Medica, vol. 73, no. 4, pp. 392–398, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Yan, S. L. Li, H. S. Chung, Y. Tam, and G. Lin, “Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatography,” Journal of Pharmaceutical and Biomedical Analysis, vol. 37, no. 1, pp. 87–95, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. T. Yi, K. S. Leung, G. H. Lu, K. Chan, and H. Zhang, “Simultaneous qualitative and quantitative analyses of the major constituents in the rhizome of Ligusticum chuanxiong using HPLC-DAD-MS,” Chemical and Pharmaceutical Bulletin, vol. 54, no. 2, pp. 255–259, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. Q. Wu and X. W. Yang, “GC-MS analysis of essential oil from rhizomes of Ligusticum chuanxiong cultivated in GAP Base for Chinese Medicinal Materials of China,” China Journal of Chinese Materia Medica, vol. 33, no. 3, pp. 276–280, 2008. View at Google Scholar · View at Scopus
  16. L. Ning, Studies on the constituents of Gastrodia elata and three medicinal plants belongs to Curculigo [Doctoral thesis], Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China, 2004.
  17. L. Wang, H. Xiao, L. Yang, and Z. T. Wang, “Two new phenolic glycosides from the rhizome of Gastrodia elata,” Journal of Asian Natural Products Research, vol. 14, no. 5, pp. 457–462, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Kobayashi and H. Mitsuhashi, “Studies on the constituents of umbelliferea plants X VII structure of three new ligustilide derivatives from Ligusticum wallichii,” Chemical & Pharmaceutical Bulletin, vol. 35, no. 12, pp. 4789–4792, 1987. View at Google Scholar
  19. Z. Q. Shi, D. F. Song, R. Q. Li et al., “Identification of effective combinatorial markers for quality standardization of herbal medicines,” Journal of Chromatography A, vol. 1345, pp. 78–85, 2014. View at Google Scholar
  20. Z. Hu, J. Yang, C. Cheng et al., “Combinatorial metabolism notably affects human systemic exposure to ginsenosides from orally administered extract of Panax notoginseng roots (Sanqi),” Drug Metabolism and Disposition, vol. 41, no. 7, pp. 1457–1469, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. H. F. Zhang, X. H. Chen, Y. S. Huo, and K. S. Bi, “RP-HPLC simultaneous determination of the contents of gastrodin , ferulic acid and 6,7-dihydroxyligustilide in Tianshu capsules under a changed UV wavelengths,” Journal of Shenyang Pharmaceutical University, vol. 29, no. 6, pp. 443–447, 2012. View at Google Scholar
  22. H. Zhang, L. Sun, X. Chen, Y. Huo, B. Yan, and K. Bi, “Simultaneous quantification of 6,7-di-hydroxyligustilide and gastrodin in rat plasma by LC-MS: application to pharmacokinetic study of Tianshu capsule,” Latin American Journal of Pharmacy, vol. 31, no. 1, pp. 112–119, 2012. View at Google Scholar · View at Scopus
  23. J. J. Liang, H. M. Gao, L. M. Chen et al., “Simultaneous determination of three constituents in Tiansu Capsule by HPLC,” Chinese Journal of Experimental Traditional Medical Formulae, vol. 19, no. 17, pp. 81–84, 2013. View at Google Scholar