Research Article

The Traditional Kampo Medicine Tokishakuyakusan Increases Ocular Blood Flow in Healthy Subjects

Table 4

Alteration of ocular blood flow and clinical variables in response to administration of kampo formula (Experiment  2).

VariableBaseline15 minutes
after treatment
30 minutes
after treatment
45 minutes
after treatment
60 minutes
after treatment
value

ControlOBF change (%) 0.49
IOP (mmHg) 0.11
SBP (mmHg) 0.98
DBP (mmHg) 0.90
MBP (mmHg) 0.96
PR (beats/min) 0.12

TSSOBF change (%) <0.01
IOP (mmHg) 0.41
SBP (mmHg) 0.98
DBP (mmHg) 0.90
MBP (mmHg) 0.45
PR (beats/min) 0.19

Data are expressed as mean ± standard deviation. The Wilcoxon signed-rank test was applied to assess differences in IOP before and after kampo administration. A one-way analysis of variance was used to assess differences in other values before and after kampo administration.