Figure 1: Antihypertensive activity of increasing doses (50, 100, and 200 mg/kg i.p.) of SeRHA, in vagotomized rats with ganglion blockage by hexamethonium chloride, pretreated with AG II i.v. Each bar represents the average of the differential of systolic (a) and diastolic (b) blood pressure with respect to the basal pressure, after AG II administration. ANOVA, post hoc Bonferroni , when compared to SeRHA 50 mg/kg represented in white bars ( ; mean ± SE).