Treatment of Acute Lymphoblastic Leukemia from Traditional Chinese Medicine

Table 2

DHFR and TS docking score of TCM candidates.

Index	TCM candidate	DHFR docking score	TS docking score
1	Adenosine triphosphate	226.6790	186.2170
2	Methyl 6-O-digalloyl-beta-D-glucopyranoside (II)	162.6260	154.1730
3	Methyl 4,6-di-O-galloyl-beta-D-glucopyranoside	153.7500	148.2880
4	Methyl 6-O-digalloyl-beta-D-glucopyranoside	151.7650	158.0350
5	Manninotriose	129.7870	114.6030
6	Forsythiaside	129.6030	27.9940
7	Isoacteoside	124.5900	30.6190
8	Rehmannioside B	119.9930	79.2920
9	Rehmannioside A	116.4330	71.3970
10	Raffinose	115.4940	134.2120
11	Cistanoside C	112.4270	—
12	Methyl 3,3,6-tri-O-galloyl-beta-D-glucopyranoside	109.9470	20.7830
13	Stachyose	107.0940	8.5760
14	Chlorogenic acid	103.8080	—
15	Jionoside D	103.5050	39.3430
16	Isochlorogenic acid	102.9470	—
17	Jionoside C	102.3940	—
18	Rutin	101.1310	78.816
*	MTX	97.0960	—
**	MTX-PGs	—	69.671

∗control.
∗∗Methotrexate polyglutamate.