Neurotrophic Signaling Factors in Brain Ischemia/Reperfusion Rats: Differential Modulation Pattern between Single-Time and Multiple Electroacupuncture Stimulation
Western blot quantification of the expression of GMFβ at days 1 and 7 of reperfusion. Representative images of western blot at day 1 (a) and day 7 (b) of reperfusion showed that GMFβ was expressed in both striatum and cortex. The level of GMFβ was notably increased in the ischemic cortex at the Rep 1 d (c). Note that single-time EA stimulation significantly reduced GMFβ expression in the ischemic striatum (c), while multiple EA stimulation had no effect on GMFβ expression at Rep 7 d (d). sham: sham-operation group; isc: ischemia group; EA: ischemia plus EA group; cor: cortex; str: striatum; Rep 1 d: day 1 of reperfusion; Rep 7 d: day 7 of reperfusion. . for each group.