Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Fig 5

Research Article

Elemene Injection Induced Autophagy Protects Human Hepatoma Cancer Cells from Starvation and Undergoing Apoptosis

Figure 5

Ele reduced the effectiveness of apatinib on H22 solid tumor in mice. The H22 bearing mice were randomized into six groups ( ): 200 mg/kg apatinib group, 75 mg/kg Ele group, 50 mg/kg Ele + 200 mg/kg apatinib group, 75 mg/kg Ele + 200 mg/kg apatinib group, 100 mg/kg Ele + 200 mg/kg apatinib group, 75 mg/kg Ele + 100 mg/kg apatinib group, 75 mg/kg Ele + 300 mg/kg apatinib group, and H22-bearing mice as negative control group (NS group). All the mice were sacrificed after 8 days of treatment. Inhibition ratio (IR) was calculated using . versus apatinib, # versus Ele.

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