Brazilian Red Propolis Induces Apoptosis-Like Cell Death and Decreases Migration Potential in Bladder Cancer Cells

Figure 5

BRP ethanolic extract increased the Bax/Bcl-2 ratio in 5637-cell line after 24 hours of treatment. The gene expression profile was determined by qRT-PCR and data were normalized using GAPDH levels. (a) Proapoptotic Bax gene expression. (b) Antiapoptotic Bcl-2 gene expression. (c) Bax/Bcl-2 ratio. Data are expressed as means ± SEM from three independent experiments. Different letters (A, B, and C) indicate significant differences between the means and () indicates difference between 100 μg/mL treated group and no treatment control group. The differences were considered significant at .

(a)

(b)

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