Herbal Medicines for the Treatment of Nonalcoholic Steatohepatitis: Current Scenario and Future Prospects

Table 4

Polyherbal therapeutic approaches available for the management of nonalcoholic steatohepatitis.

Name	Composition	Model	Mode of action	Reference
Dangfei Liganning Capsules	Herba Swertiae and Fructus Silybi	HFD fed rats	By reducing oxidative stress	[65]
Danning Tablet	Rheum rhabarbarum L, Polygonum sachalinense,and Citrus aurantium	NAFLD patients	Not defined	[66]
Fuzheng Huayu recipe (FZHY)	Semen persicae, Radix Salvia Miltiorrhizae, Gynostemma pentaphyllammak, Cordyceps, Pollen pini,and Fructus schisandrae chinensis	HFD fed C57BL/6J mice	Regulation of oxidative stress, inflammation, and fibrogenesis	[67]
Keishibukuryogan (KBG, TJ-25),	Cinnamomum cassia Blume, Paeonia lactiflora Pallas, Prunus persica Batsch, Poria cocos Wolf,and Paeonia suffruticosa Andrews	HFD fed white rabbits	Not defined	[68]
Liv-Pro-08	Nigella sativa, Entada pursaetha, and Ficus glomerata	HFD fed rats	Not defined	[69]
Orengedokuto (OGT, TJ-15)	Scutellaria baicalensis Georgi, Coptis japonica Makino, Gardenia jasminoides Ellis, and Phellodendron amurense Ruprecht	HFD fed white rabbits	Not defined	[68]
Ping-tang Recipe	Rhizoma alismatis, Rhizoma atractylodis macrocephalae, Rheum palmatum L., and Crataegus pinnatifida	HFD fed rats	Modulation of AMPK signaling pathway	[70]
Qianggan Capsule	Herba Artemisia, Radix Paeoniae lactiflora Alba, Radix Astragalus membranaceus, Rhizoma Polygonatum, Fructus Crataegus, Radix Glycyrrhiza, Radix Isati-dis, Radix Salviae Miltiorrhiza, Radix Codonopsis Pilosula, Radix Re-hmannia, Massa Fermentata Medicina-lis, Radix Angelica Sinensis, Radix Curcuma, Rhizoma Alisma Ori-rhizome, Rhizoma Dioscorea, and Radix Gentiana Macrophylla	NAFLD patients	Not defined	[71]
Qushi Huayu Decoction	Artemisia capillaries Thunb, Rhizoma Polygoni Cuspidati, Hypericum japonicum Thunb, Rhizoma Curcumae Longae, and Gardenia jasminoides Ellis	HFD fed rats	Regulation of Free fatty acid oxidation	[72]
QuYuHuaTanTongLuo Decoction	Radix Bupleuri, Radix Scutellariae, Rhizoma Pinelliae, Radix Codonopsis Pilosulae, Radix Glycyrrhizae Praeparata, Fructus Ziziphi Jujubae, Rhizoma Polygoni Cuspidati, Radix Morindae Officinalis, and Herba Hedyotis Diffusae	NASH patients	Not defined	[73]
RGTC	Vitis vinifera, Camellia sinensis, and l-carnitine	HFD fed C57BL/6J mice	Not defined	[74]
RISC	Vitis vinifera, Glycine max isoflavone and L-carnitine	HFD fed C57BL/6J mice	Not defined	[75]
Shosaikoto; (SST, TJ-9)	Bupleurum falcatum Linne, Pinellia rhizome Breitenbach, Scutellaria baicalensis Georgi, Zizyphus rhizome Miller, Panax ginseng C.A. Meyer, Glycyrrhiza uralensis Fischer,and Zingiber officinale Roscoe	HFD fed white rabbits	Not defined	[68]
Sinai San decoction	Radix Bupleuri, Radix Paeoniae, Fructus Aurantii Immaturus, and Radix Glycyrrhizae	HFD fed rats	Not defined	[76]
Tiaozhi Yanggan Decoction	Bupleurum chinense DC, Curcuma longa, Peonia albaflora, Crataegus tourn, Alisma triviale, Cassia tora, Polygonum sachalinense, Rheum rhabarbarum L, Semen Persicae, Salvia miltiorrhiza, Raphanus sativus, and Citrus tangerina	NAFLD patients	Not defined	[77]
Yinchenhao Decoction	Artemisia capillaries Thunb, Gardenia jasminoides Ellis, and Rheum	HFD fed rats	Reduced fatty acid oxidation	[78]
Yo jyo hen shi ko (YHK)	Panax pseudoginseng, Eucommia ulmoides, Polygonati rhizome, and Glycyrrhiza glabra	NASH patients	Not defined	[79]