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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 731395, 10 pages
http://dx.doi.org/10.1155/2014/731395
Research Article

The Effect of Electroacupuncture on the Extracellular Matrix Synthesis and Degradation in a Rabbit Model of Disc Degeneration

1Department of Neurobiology, School of Basic Medicine, Tongji Medical College of Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030, China
2Department of Acupuncture & Moxibustion, Wuhan Hospital of Integrated Chinese & Western Medicine, Tongji Medical College of Huazhong University of Science & Technology, 215 Zhongshan Road, Wuhan 430022, China

Received 19 February 2014; Revised 24 April 2014; Accepted 6 May 2014; Published 27 May 2014

Academic Editor: Cheng Ke

Copyright © 2014 Guo-fu Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. B. J. Andersson, “Epidemiological features of chronic low-back pain,” The Lancet, vol. 354, no. 9178, pp. 581–585, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. M. C. Battie, T. Videman, L. E. Gibbons, L. D. Fisher, H. Manninen, and K. Gill, “Determinants of lumbar disc degeneration: a study relating lifetime exposures and magnetic resonance imaging findings in identical twins,” Spine, vol. 20, no. 24, pp. 2601–2612, 1995. View at Google Scholar · View at Scopus
  3. J. C. Lotz, O. K. Colliou, J. R. Chin, N. A. Duncan, and E. Liebenberg, “Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study,” Spine, vol. 23, no. 23, pp. 2493–2506, 1998. View at Publisher · View at Google Scholar · View at Scopus
  4. J. C. Lotz, A. Staples, A. Walsh, and A. H. Hsieh, “Mechanobiology in intervertebral disc degeneration and regeneration,” in Proceedings of the 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 7, p. 5459, 2004.
  5. S. R. Pye, D. M. Reid, J. E. Adams, A. J. Silman, and T. W. O'Neill, “Influence of weight, body mass index and lifestyle factors on radiographic features of lumbar disc degeneration,” Annals of the Rheumatic Diseases, vol. 66, no. 3, pp. 426–427, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. Zhang, H. S. An, C. Tannoury, E. J.-M. A. Thonar, M. K. Freedman, and D. G. Anderson, “Biological treatment for degenerative disc disease: implications for the field of physical medicine and rehabilitation,” American Journal of Physical Medicine and Rehabilitation, vol. 87, no. 9, pp. 694–702, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Lam, P. Curry, and R. Galvin, “The effectiveness of acupuncture for non-specific chronic low back pain: a systematic review and meta-analysis,” Spine, vol. 38, no. 24, pp. 2124–2138, 2013. View at Google Scholar
  8. “NIH Consensus Conference. Acupuncture,” The Journal of the American Medical Association, vol. 280, no. 17, pp. 1518–1524, 1998.
  9. A. Li and T. J. Kaptchuk, “The case of acupuncture for chronic low back pain: when efficacy and comparative effectiveness conflict,” Spine, vol. 36, no. 3, pp. 181–182, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. N. Goldman, M. Chen, T. Fujita et al., “Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture,” Nature Neuroscience, vol. 13, no. 7, pp. 883–888, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. J.-S. Han, “Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies,” Trends in Neurosciences, vol. 26, no. 1, pp. 17–22, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. L. Chen, J. Zhang, F. Li et al., “Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats,” Journal of Pain, vol. 10, no. 7, pp. 732–739, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. J. H. Neufeld, “Induced narrowing and back adaptation of lumbar intervertebral discs in biomechanically stressed rats,” Spine, vol. 17, no. 7, pp. 811–816, 1992. View at Google Scholar · View at Scopus
  14. P. J. Roughley, “Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix,” Spine, vol. 29, no. 23, pp. 2691–2699, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. T. R. Oegema Jr., “Biochemistry of the intervertebral disc,” Clinics in Sports Medicine, vol. 12, no. 3, pp. 419–439, 1993. View at Google Scholar · View at Scopus
  16. T. R. Oegema Jr., “The role of disc cell heterogeneity in determining disc biochemistry: a speculation,” Biochemical Society Transactions, vol. 30, no. 6, pp. 839–844, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. J. E. Scott, T. R. Bosworth, A. M. Cribb, and J. R. Taylor, “The chemical morphology of age-related changes in human intervertebral disc glycosaminoglycans from cervical, thoracic and lumbar nucleus pulposus and annulus fibrosus,” Journal of Anatomy, vol. 184, no. 1, pp. 73–82, 1994. View at Google Scholar · View at Scopus
  18. K. Yamada, “The dynamics of experimental posture. Experimental study of intervertebral disk herniation in bipedal animals,” Clinical Orthopaedics, vol. 25, pp. 20–31, 1962. View at Google Scholar · View at Scopus
  19. J. A. M. V. C. Buckwalter, S. D. Boden, D. R. Eyre, and M. Weidenbaum, “Intervertebral disk structure, composition, and mechanical function,” in Orthopaedic Basic Sciences: Biology and Biomechanics of the Musculoskeletal System, American Academy of Orthopaedic Surgeons, Rosemont, Ill, USA, 2000. View at Google Scholar
  20. J. D. Cassidy, K. Yong-Hing, W. H. Kirkaldy-Willis, and A. A. Wilkinson, “A study of the effects of bipedism and upright posture on the lumbosacral spine and paravertebral muscles of the Wistar rat,” Spine, vol. 13, no. 3, pp. 301–308, 1988. View at Google Scholar · View at Scopus
  21. H. Gloobe and H. Nathan, “Osteophyte formation in experimental bipedal rats,” Journal of Comparative Pathology, vol. 83, no. 1, pp. 133–141, 1973. View at Google Scholar · View at Scopus
  22. M. W. Kroeber, F. Unglaub, H. Wang et al., “New in vivo animal model to create intervertebral disc degeneration and to investigate the effects of therapeutic strategies to stimulate disc regeneration,” Spine, vol. 27, no. 23, pp. 2684–2690, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. C. W. A. Pfirrmann, A. Metzdorf, M. Zanetti, J. Hodler, and N. Boos, “Magnetic resonance classification of lumbar intervertebral disc degeneration,” Spine, vol. 26, no. 17, pp. 1873–1878, 2001. View at Publisher · View at Google Scholar · View at Scopus
  24. M. P. Vincenti and C. E. Brinckerhoff, “Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors,” Arthritis Research, vol. 4, no. 3, pp. 157–164, 2002. View at Publisher · View at Google Scholar · View at Scopus
  25. H. Uchinami, E. Seki, D. A. Brenner, and J. D'Armiento, “Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis,” Hepatology, vol. 44, no. 2, pp. 420–429, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. J. Clouet, C. Vinatier, C. Merceron et al., “The intervertebral disc: from pathophysiology to tissue engineering,” Joint Bone Spine, vol. 76, no. 6, pp. 614–618, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. N. S. Kalson, S. Richardson, and J. A. Hoyland, “Strategies for regeneration of the intervertebral disc,” Regenerative Medicine, vol. 3, no. 5, pp. 715–729, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. C. K. Lee, “Accelerated degeneration of the segment adjacent to a lumbar fusion,” Spine, vol. 13, no. 3, pp. 375–377, 1988. View at Google Scholar · View at Scopus
  29. S. Sobajima, J. F. Kompel, J. S. Kim et al., “A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology,” Spine, vol. 30, no. 1, pp. 15–24, 2005. View at Google Scholar · View at Scopus
  30. J. S. Thalgott, T. J. Albert, A. R. Vaccaro et al., “A new classification system for degenerative disc disease of the lumbar spine based on magnetic resonance imaging, provocative discography, plain radiographs and anatomic considerations,” Spine Journal, vol. 4, no. 6, pp. S167–S172, 2004. View at Publisher · View at Google Scholar · View at Scopus
  31. C. Weiler, A. Nerlich, J. Zipperer, B. Bachmeier, and N. Boos, “2002 SSE award competition in basic science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption,” European Spine Journal, vol. 11, no. 4, pp. 308–320, 2002. View at Publisher · View at Google Scholar · View at Scopus
  32. G. Cs-Szabo, D. Ragasa-San Juan, V. Turumella, K. Masuda, E. J.-M. A. Thonar, and H. S. An, “Changes in mrna and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration,” Spine, vol. 27, no. 20, pp. 2212–2219, 2002. View at Publisher · View at Google Scholar · View at Scopus
  33. J. P. G. Urban and S. Roberts, “Degeneration of the intervertebral disc,” Arthritis Research and Therapy, vol. 5, no. 3, pp. 120–130, 2003. View at Google Scholar · View at Scopus
  34. I. A. F. Stokes and J. C. Iatridis, “Mechanical conditions that accelerate intervertebral disc degeneration: overload versus immobilization,” Spine, vol. 29, no. 23, pp. 2724–2732, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Kroeber, F. Unglaub, T. Guehring et al., “Effects of controlled dynamic disc distraction on degenerated intervertebral discs: an in vivo study on the rabbit lumbar spine model,” Spine, vol. 30, no. 2, pp. 181–187, 2005. View at Google Scholar
  36. T. Guehring, G. W. Omlor, H. Lorenz et al., “Stimulation of gene expression and loss of anular architecture caused by experimental disc degeneration—an in vivo animal study,” Spine, vol. 30, no. 22, pp. 2510–2515, 2005. View at Publisher · View at Google Scholar · View at Scopus
  37. P. Goupille, M. I. V. Jayson, J.-P. Valat, and A. J. Freemont, “Matrix metalloproteinases: the clue to intervertebral disc degeneration?” Spine, vol. 23, no. 14, pp. 1612–1626, 1998. View at Publisher · View at Google Scholar · View at Scopus
  38. M. Doita, T. Kanatani, T. Ozaki, N. Matsui, M. Kurosaka, and S. Yoshiya, “Influence of macrophage infiltration of herniated disc tissue on the production of matrix metalloproteinases leading to disc resorption,” Spine, vol. 26, no. 14, pp. 1522–1527, 2001. View at Publisher · View at Google Scholar · View at Scopus
  39. B. Shen, J. Melrose, P. Ghosh, and T. K. F. Taylor, “Induction of matrix metalloproteinase-2 and -3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin-1β: a potential pathway of disc degeneration,” European Spine Journal, vol. 12, no. 1, pp. 66–75, 2003. View at Google Scholar · View at Scopus
  40. S. Razaq, R. J. Wilkins, and J. P. G. Urban, “The effect of extracellular pH on matrix turnover by cells of the bovine nucleus pulposus,” European Spine Journal, vol. 12, no. 4, pp. 341–349, 2003. View at Publisher · View at Google Scholar · View at Scopus
  41. M. B. Goldring, M. Otero, K. Tsuchimochi, K. Ijiri, and Y. Li, “Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism,” Annals of the Rheumatic Diseases, vol. 67, supplement 3, pp. iii75–iii82, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. C. L. le Maitre, A. J. Freemont, and J. A. Hoyland, “Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration,” Arthritis Research and Therapy, vol. 9, no. 3, article R45, 2007. View at Publisher · View at Google Scholar · View at Scopus
  43. H. Nagase and M. Kashiwagi, “Aggrecanases and cartilage matrix degradation,” Arthritis Research and Therapy, vol. 5, no. 2, pp. 94–103, 2003. View at Google Scholar · View at Scopus
  44. R. Visse and H. Nagase, “Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry,” Circulation Research, vol. 92, no. 8, pp. 827–839, 2003. View at Publisher · View at Google Scholar · View at Scopus
  45. F. X. Gomis-Ruth, K. Maskos, M. Betz et al., “Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1,” Nature, vol. 389, pp. 77–81, 1997. View at Google Scholar
  46. S. D. Boden, J. Kang, H. Sandhu, and J. G. Heller, “Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial 2002 volvo award in clinical studies,” Spine, vol. 27, no. 23, pp. 2662–2673, 2002. View at Publisher · View at Google Scholar · View at Scopus
  47. D.-J. Kim, S.-H. Moon, H. Kim et al., “Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells,” Spine, vol. 28, no. 24, pp. 2679–2684, 2003. View at Publisher · View at Google Scholar · View at Scopus